Antibiotic powder
Antibiotic powder
OXYZAND® 50
Oxytetracycline 50% Feed Premix
Composition
| Ingredient | Amount | Unit |
|---|---|---|
| Each gram of OXYZAND® 50 contains : | ||
| oxytetracycline | 500 | mg |
Mechanism of action
Oxytetracycline is a broad-spectrum antibiotic of the tetracycline class that is predominantly bacteriostatic. It binds reversibly to the 30S subunit of the bacterial ribosome and prevents the binding of aminoacyl-tRNA to the A site of the ribosome–mRNA complex. Consequently, the incorporation of amino acids into the growing chain and bacterial protein synthesis are inhibited, resulting in cessation of bacterial growth.
Oxytetracycline has greater activity against actively multiplying microorganisms and is more active at pH 6 to 6.5. Oxytetracycline is effective against susceptible strains of a wide range of aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as certain Mycoplasma spp., Rickettsia spp., and Chlamydia spp.
Susceptibility to oxytetracycline may vary among bacterial species and strains, and resistance has been reported in bacteria such as Escherichia coli, Proteus spp., Klebsiella spp., and Pseudomonas spp.
Oxytetracycline has greater activity against actively multiplying microorganisms and is more active at pH 6 to 6.5. Oxytetracycline is effective against susceptible strains of a wide range of aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as certain Mycoplasma spp., Rickettsia spp., and Chlamydia spp.
Susceptibility to oxytetracycline may vary among bacterial species and strains, and resistance has been reported in bacteria such as Escherichia coli, Proteus spp., Klebsiella spp., and Pseudomonas spp.
Target species
Poultry
Indications
OXYZAND® 50 is indicated for the control and treatment of colibacillosis, chronic respiratory disease (CRD) caused by Mycoplasma susceptible to oxytetracycline, salmonellosis, fowl cholera, infectious coryza, staphylococcal infections, chlamydiosis, and secondary bacterial infections associated with hexamitiasis and bluecomb disease in turkeys.
Packaging
1 kg multilayer aluminium sachets
Storage Conditions
Store in a dry place below 25°C, protected from direct light, in the original packaging. Once opened, keep the sachet tightly closed.
Dosage and Administration
200–500 g of OXYZAND® 50 per ton of feed for 5 to 7 consecutive days.
- As directed by the veterinarian.
- As directed by the veterinarian.
Withdrawal period
Meat and offal: 7 days
Contraindications
Do not use in laying hens producing eggs for human consumption.
Precautions
Keep out of reach of children.
Drug interactions
Concomitant use of OXYZAND® 50 with quinolones, aminoglycosides, penicillins, and cephalosporins, is not recommended due to competitive antagonism and reduced antimicrobial efficacy.
Absorption of OXYZAND® 50 is reduced when this drug is administered concomitantly with divalent or trivalent cations such as aluminum, calcium, magnesium, and iron, or with products containing calcium, magnesium, and iron.
Absorption of OXYZAND® 50 is reduced when this drug is administered concomitantly with divalent or trivalent cations such as aluminum, calcium, magnesium, and iron, or with products containing calcium, magnesium, and iron.
Oxytetracycline 50% Feed Premix