Antibiotic powder
Antibiotic powder
TiamoZand®
100 g multilayer aluminium sachets
Composition
| Ingredient | Amount | Unit |
|---|---|---|
| Each gram of TiamoZand® contains : | ||
| tiamulin hydrogen fumarate | 450 |
Mechanism of action
Tiamulin is a semisynthetic antibiotic of the pleuromutilin group that is primarily bacteriostatic and, at high concentrations, may exert bactericidal activity against some susceptible microorganisms. Tiamulin specifically binds to the 50S subunit of the bacterial ribosome at the peptidyl transferase center and inhibits bacterial protein synthesis by interfering with tRNA positioning and peptide bond formation.
Tiamulin is active against many susceptible strains of Mycoplasma spp., particularly Mycoplasma gallisepticum and Mycoplasma synoviae, and against some Gram-positive bacteria such as Streptococcus and Staphylococcus species, some Gram-negative bacteria such as Avibacterium paragallinarum, Pasteurella, and Campylobacter, anaerobic bacteria such as Clostridium perfringens, spirochetes, and other susceptible microorganisms.
Tiamulin is active against many susceptible strains of Mycoplasma spp., particularly Mycoplasma gallisepticum and Mycoplasma synoviae, and against some Gram-positive bacteria such as Streptococcus and Staphylococcus species, some Gram-negative bacteria such as Avibacterium paragallinarum, Pasteurella, and Campylobacter, anaerobic bacteria such as Clostridium perfringens, spirochetes, and other susceptible microorganisms.
Target species
Poultry
Indications
TiamoZand® is indicated for the treatment of infections caused by tiamulin-susceptible Mycoplasma in the respiratory tract and joints.
Packaging
100 g multilayer aluminium sachets
Storage Conditions
Store in a dry place below 25°C, protected from direct light, in the original packaging. Once opened, keep the sachet tightly closed.
Dosage and Administration
25 mg of tiamulin hydrogen fumarate per kg of body weight, equivalent to 100 g of TiamoZand® in 200 liters of drinking water, for 3 to 5 consecutive days.
- As directed by a veterinarian.
- As directed by a veterinarian.
Withdrawal period
Broilers: 2 days
Turkey: 5 days
Eggs: 0 days
Turkey: 5 days
Eggs: 0 days
Contraindications
No specific cases have been reported at the recommended dosages.
Precautions
Medicated drinking water should be used within 24 hours.
Keep out of reach of children.
Keep out of reach of children.
Drug interactions
Avoid concomitant use of TiamoZand® with ionophore coccidiostats such as monensin, salinomycin, and narasin. A 7-day interval between administration of TiamoZand® and these drugs is recommended.
100 g multilayer aluminium sachets