Antibiotic powder
Antibiotic powder
TyloZand® 25
Tylosin Phosphate 25% Granulated Premix
Composition
| Ingredient | Amount | Unit |
|---|---|---|
| Each gram of TyloZand® 25 contains : | ||
| tylosin phosphate | 250 | mg |
Mechanism of action
Tylosin is a macrolide antibiotic that acts mainly as a bacteriostatic agent. By reversibly binding to the 50S ribosomal subunit of susceptible bacteria, it inhibits bacterial protein synthesis.
Tylosin is mainly effective against Gram-positive bacteria, including streptococci and staphylococci. It also has activity against some susceptible Gram-negative bacteria, although its activity against this group is limited. Tylosin also shows good activity against Mycoplasma spp.
Some laboratory and experimental studies have reported the modulatory effects of tylosin on immune responses and inflammatory processes.
Tylosin is mainly effective against Gram-positive bacteria, including streptococci and staphylococci. It also has activity against some susceptible Gram-negative bacteria, although its activity against this group is limited. Tylosin also shows good activity against Mycoplasma spp.
Some laboratory and experimental studies have reported the modulatory effects of tylosin on immune responses and inflammatory processes.
Target species
Poultry
Indications
TyloZand® 25 is indicated for the control and treatment of infections caused by microorganisms susceptible to tylosin in poultry, including chronic respiratory disease (CRD) caused by Mycoplasma gallisepticum and necrotic enteritis caused by Clostridium perfringens in broilers, laying pullets, and turkeys.
Packaging
1 kg multilayer aluminium sachets
Storage Conditions
Store in a dry place below 25°C, protected from direct light, in the original packaging. Once opened, keep the sachet tightly closed.
Dosage and Administration
For the control and treatment of chronic respiratory disease (CRD)
127 mg of tylosin phosphate per kg of body weight, equivalent to 4.4 kg of TyloZand® 25 per ton of feed, daily for the first 5 days of life, followed by re-administration for 48 hours at 3 to 4 weeks of age.
For the control and treatment of necrotic enteritis
10 to 20 mg of tylosin phosphate per kg of body weight, equivalent to 350 to 700 g of TyloZand® 25 per ton of feed, for 7 consecutive days.
First mix the required amount of TyloZand® 25 with 50 kg of supplement or feed, then add the resulting mixture to the final feed and mix again.
- As directed by a veterinarian.
127 mg of tylosin phosphate per kg of body weight, equivalent to 4.4 kg of TyloZand® 25 per ton of feed, daily for the first 5 days of life, followed by re-administration for 48 hours at 3 to 4 weeks of age.
For the control and treatment of necrotic enteritis
10 to 20 mg of tylosin phosphate per kg of body weight, equivalent to 350 to 700 g of TyloZand® 25 per ton of feed, for 7 consecutive days.
First mix the required amount of TyloZand® 25 with 50 kg of supplement or feed, then add the resulting mixture to the final feed and mix again.
- As directed by a veterinarian.
Withdrawal period
Broilers: 1 day
Turkeys: 5 days
Turkeys: 5 days
Contraindications
Do not use in laying hens producing eggs for human consumption.
Precautions
TyloZand® 25 should be mixed uniformly into the feed. Protective clothing and a dust mask should be worn when transporting and handling the product.
Keep out of the reach of children.
Keep out of the reach of children.
Drug interactions
Concomitant use of TyloZand® 25 with florfenicol, lincosamides, other macrolides, penicillins, and cephalosporins is not recommended due to antagonism and reduced antimicrobial efficacy.
Tylosin Phosphate 25% Granulated Premix