Therapeutic support
Therapeutic support
ASPIRAZAND®
Aspirin + Vitamin C Water-Soluble Powder
Composition
| Ingredient | Amount | Unit |
|---|---|---|
| Each gram of ASPIRAZAND® contains : | ||
| acetylsalicylic acid (aspirin) | 250 | mg |
| ascorbic acid (vitamin C) | 20 | mg |
Mechanism of action
Aspirin (acetylsalicylic acid) is a non-steroidal anti-inflammatory drug (NSAID) that reduces the synthesis of prostaglandins and thromboxane A₂ primarily through the irreversible acetylation and inhibition of cyclooxygenase (COX) enzymes, especially COX-1. The reduction of these mediators produces the analgesic, anti-inflammatory, and antipyretic effects of aspirin. By inhibiting COX-1 in platelets, aspirin also reduces thromboxane A₂ formation and platelet aggregation. The intensity and duration of these effects may vary among species.
Ascorbic acid (vitamin C) is a water-soluble vitamin and antioxidant that plays a role in maintaining oxidative balance, collagen synthesis, the integrity of connective tissue and blood vessels, and normal immune function. Under conditions of increased physiological demand and stress—including heat stress, transport, vaccination, and disease—vitamin C supplementation may be used as supportive therapy.
Ascorbic acid (vitamin C) is a water-soluble vitamin and antioxidant that plays a role in maintaining oxidative balance, collagen synthesis, the integrity of connective tissue and blood vessels, and normal immune function. Under conditions of increased physiological demand and stress—including heat stress, transport, vaccination, and disease—vitamin C supplementation may be used as supportive therapy.
Target species
Poultry, calves, lambs and horses.
Indications
Poultry
Used to control fever, inflammation, pain, and loss of appetite associated with viral and bacterial diseases, including chronic respiratory disease (CRD), colibacillosis, infectious coryza, infectious bronchitis, Newcastle disease, and influenza. It may also be used as supportive therapy under stressful conditions, such as heat stress, transportation, and vaccination, as well as in conditions predisposing poultry to ascites.
Calves and lambs
Used as an analgesic, antipyretic, and anti-inflammatory agent for the symptomatic treatment of conditions accompanied by pain, fever, and inflammation, including muscle and joint pain and inflammatory diseases. It may also be used as supportive therapy under stressful conditions.
Horses
Used as an analgesic, antipyretic, and anti-inflammatory agent for the symptomatic treatment of pain and inflammation. In horses, it may be used as supportive therapy for laminitis and certain conditions associated with musculoskeletal pain and inflammation.
Used to control fever, inflammation, pain, and loss of appetite associated with viral and bacterial diseases, including chronic respiratory disease (CRD), colibacillosis, infectious coryza, infectious bronchitis, Newcastle disease, and influenza. It may also be used as supportive therapy under stressful conditions, such as heat stress, transportation, and vaccination, as well as in conditions predisposing poultry to ascites.
Calves and lambs
Used as an analgesic, antipyretic, and anti-inflammatory agent for the symptomatic treatment of conditions accompanied by pain, fever, and inflammation, including muscle and joint pain and inflammatory diseases. It may also be used as supportive therapy under stressful conditions.
Horses
Used as an analgesic, antipyretic, and anti-inflammatory agent for the symptomatic treatment of pain and inflammation. In horses, it may be used as supportive therapy for laminitis and certain conditions associated with musculoskeletal pain and inflammation.
Packaging
1000 g multilayer aluminium sachets
Storage Conditions
Store in a dry place below 25°C, protected from direct light, in the original packaging. Once opened, keep the sachet tightly closed.
Dosage and Administration
Poultry
1 kg of ASPIRAZAND® per 1000 liters of drinking water.
Horses
10 to 20 grams of ASPIRAZAND® per 100 kg of body weight, orally, depending on the type of disease and the animal’s condition.
Calves and lambs
2 gr of ASPIRAZAND® per 10 kg of body weight.
-As directed by a veterinarian.
1 kg of ASPIRAZAND® per 1000 liters of drinking water.
Horses
10 to 20 grams of ASPIRAZAND® per 100 kg of body weight, orally, depending on the type of disease and the animal’s condition.
Calves and lambs
2 gr of ASPIRAZAND® per 10 kg of body weight.
-As directed by a veterinarian.
Withdrawal period
Withdrawal period
Meat and offal: 2 days
Eggs: 0 days
Milk: 0 days
Meat and offal: 2 days
Eggs: 0 days
Milk: 0 days
Contraindications
Do not use in animals with known hypersensitivity to salicylates, those suffering from peptic ulcers, or those at risk of bleeding.
Precautions
• Concomitant use of ASPIRAZAND® with sulfonamides should be undertaken with caution because of the potential for competition for plasma protein binding.
• Remove the desiccant sachet from the package before use.
• Medicated drinking water should be used within 12 hours.
• Keep out of reach of children.
• Remove the desiccant sachet from the package before use.
• Medicated drinking water should be used within 12 hours.
• Keep out of reach of children.
Drug interactions
Concomitant use of ASPIRAZAND® with other NSAIDs and corticosteroids should be avoided. Concurrent use of ASPIRAZAND® with anticoagulants should only be undertaken under veterinary supervision.
Aspirin + Vitamin C Water-Soluble Powder