Antibiotic solution
Antibiotic solution
Florzand®
Florfenicol 10% Oral Solution
Composition
| Ingredient | Amount | Unit |
|---|---|---|
| Each ml of Florzand® contains : | ||
| florfenicol | 100 | mg |
Mechanism of action
Florfenicol is a synthetic, broad-spectrum antibiotic belonging to the amphenicol group. It acts by binding to the 50S ribosomal subunit of susceptible bacteria and inhibiting the peptidyl transferase enzyme, thereby interfering with bacterial protein synthesis and inhibiting bacterial growth. Florfenicol is primarily bacteriostatic, although bactericidal activity may occur against certain susceptible bacteria.
Florfenicol has a broad spectrum of activity against susceptible Gram-positive and Gram-negative bacteria. It is active against susceptible bacterial pathogens associated with respiratory and gastrointestinal infections in poultry, including Streptococcus spp., Staphylococcus spp., Clostridium spp., Escherichia coli, Pasteurella spp., and Avibacterium paragallinarum.
Florfenicol has a broad spectrum of activity against susceptible Gram-positive and Gram-negative bacteria. It is active against susceptible bacterial pathogens associated with respiratory and gastrointestinal infections in poultry, including Streptococcus spp., Staphylococcus spp., Clostridium spp., Escherichia coli, Pasteurella spp., and Avibacterium paragallinarum.
Target species
Broilers and Breeders
Indications
Florzand® is indicated for the treatment of infections caused by microorganisms susceptible to florfenicol, including staphylococcal infections, colibacillosis, pasteurellosis, infectious coryza, and respiratory tract infections caused by Ornithobacterium rhinotracheale.
Packaging
1 L polyethylene bottles
Storage Conditions
Store below 25°C, protected from direct light, in the original packaging. After opening, keep the container cap tightly closed. Protect from freezing.
Dosage and Administration
Administer 20–30 mg of florfenicol per kg of body weight, or use the following age-based dosage:
• 1–2 weeks of age: 1000 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
• 3–4 weeks of age: 1300 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
• Over 5 weeks of age: 1700 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
As directed by veterinarian.
• 1–2 weeks of age: 1000 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
• 3–4 weeks of age: 1300 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
• Over 5 weeks of age: 1700 ml of Florzand® per 1000 L of drinking water for 3–5 consecutive days.
As directed by veterinarian.
Withdrawal period
Meat and offal: 5 days
Contraindications
Do not use in laying hens producing eggs for human consumption.
Precautions
Medicated drinking water should be used within 24 hours.
Keep out of reach of children.
Keep out of reach of children.
Drug interactions
Concomitant use of Florzand® with macrolides, lincosamides, fluoroquinolones, penicillins, and cephalosporins is not recommended due to antagonism and reduced antimicrobial efficacy.
Florfenicol 10% Oral Solution